I. Basics

BAKER BROS. ADVISORS LP is a New York-based hedge fund management firm founded in 2000 by brothers Julian and Felix Baker, best known for its concentrated focus on biotechnology and healthcare investing. It manages a large institutional portfolio, with recent public data showing roughly $17.1 billion in disclosed 13F holdings and 86 positions, and it is widely regarded as one of the most influential healthcare-focused investors in the market.

Julian Baker is the cofounder and managing partner of Baker Bros. Advisors LP, the biotechnology-focused investment firm he launched with his brother in 2000; he is known for long-term investing in life-sciences companies and has also served on the boards of several biopharma firms.

Felix Baker is the cofounder and managing member of Baker Bros. Advisors LP, with a Ph.D. in immunology from Stanford; he also focuses on biotechnology investing and serves on the boards of multiple biotech companies, reflecting the firm’s deep specialization in the sector.

II. Letters & Presentations

Nil

III. Live "significant" companies

Companies with fund stakes involved in activist actions such as 13D filing(s) or proxy campaign(s).